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Bio

Timothy Maher, PhD
Professor of Pharmacology
Associate Dean of Graduate Studies- School of Pharmacy

Department/Office
School of Pharmacy - W315

Contact
timothy.maher@mcphs.edu
(P)617.732.2940


Schools
School of Pharmacy - Boston

Programs
Pharmaceutical Sciences (BS)
Pharmaceutics (MS)
Pharmacology (MS/PhD)
Pharmacology & Toxicology (BS)

Academic and Administrative Appointments
Chair, Department of Pharmaceutical Sciences
Associate Dean for Graduate Studies
Sawyer Professor of Pharmaceutical Sciences


Education
PhD, Massachusetts College of Pharmacy and Health Sciences
BS (Honors), Boston State College


Areas of Teaching
Pharmacology
Neuroscience
Nutrition


Scholarly Interests
Effects of nutrients on central nervous system neurotransmission
Amino acid neurotransmission in the central nervous system
Gamma-hydroxy butyric acid (GHB) and date-rape drugs
Pharmacological interventions following stroke and head injury
Heavy metal toxicity in early development
Microdialysis
Central nervous system regulation of cardiovascular function
Nasal drug administration
Pharmacologic control of appetitive behaviors
Oxidative stress and DNA adduct formation


Peer-Reviewed Articles & Book Chapters
Ally, A., Maher, T.J.: Transient middle cerebral artery occlusion and reperfusion alters inducible NOS expression within the ventrolateral medulla and modulates cardiovascular function during static exercise. Can. J. Physiol. Pharmacol. 89(9):639-646, 2011.

Li, Y., Kim, J., Buckett, P.D., Böhlke, M., Maher, T.J.,Wessling-Resnick, M.: Severe post-natal iron deficiency alters emotional behavior and dopamine levels in the prefrontal cortex of young male rats. J. Nutr. 141:2133-2138, 2011.

Yang, P.S., Kim, H., Lee, W., Bohlke, M., Park, S., Maher, T.J., Yoo, S-S.: Transcranial focused ultrasound to the thalamus reduces extracellular GABA level in rats. Neuropsychobiol. 65:153-160, 2012.

Abdelhafez, O.M., Amin, K.M., Ali, H.I., Maher, T.J., Batran, R.Z.: Dopamine release and molecular modeling study of some coumarin derivatives. Neurochem. Int. 59(6):906-912, 2011.

Kim, J., Buckett, P.D., Bohlke, M., Thompson, K.J., Takahashi, M., Maher, T.J., Wessling-Resnick, M.: Olfactory administration of manganese improves motor function deficits associated with iron deficiency. PLoS One 7:e33533, 2012.

Betharia, S., Maher, T.J.: Neurobehavioral effects of lead and manganese individually and in combination in developmentally-exposed rats. Neurotoxicology 33(5):1117-1127, 2012.

Towiwat, P., Phattanarudee, S., Maher, T.J.: Comparative study of equimolar doses of GHB, 1,4-BD and GBL on catalepsy after acute and chronic administration. Food Chem. Toxicol. 51:337-42, 2013.

Nofal, Z.M., Soliman, E.A., Abd El-Karim, S.S., El-Zahar, M.I., Srour, A.M., Sethumadhavan, S., Maher, T.J.: Synthesis of some new benzimidazole-thiazole derivatives as anticancer agents. J. Heterocycl. Chem. (online 8 May 2014. DOI: 10:1002/jhet.1886).

Phattanarudee, S., Towiwat, P., Maher, T.J., Ally, A.: Effects of a nitric oxide precursor on cardiovascular responses and neurotransmission during static exercise following ischemic stroke. Can. J. Physiol. Pharmacol. 91(7):510-520, 2013.

Almukadi, H., Wu, H., Böhlke, M., Kelley, C.J., Maher, T.J., Pino-Figueroa, A.: The macamide N-3-methoxybenzyl-linoleamide is a time-dependent fatty acid amide hydrolase (FAAH) inhibitor. Molec. Neurobiol. 48: 333-339, 2013. DOI 10.1007/s12035-013-8499-2.

Wu, H., Kelley, C.J., Pino-Figueroa, A., Vu, H.D., Maher, T.J.: Macamides and synthetic analogs as in vitro fatty acid amide inhibitors. Bioorg. Med. Chem. 21(17):5188-5197, 2013.

Towiwat, P., Phatanarudee, S., Maher, T.J., Ally, A.: Modulation of inducible nitric oxide synthase (iNOS) expression and cardiovascular responses during static exercise following iNOS antagonism within the ventrolateral medulla. Molec. Cell. Biochem. 398:185-194, 2015 (DOI 10.1007/s11010-014-2218-9).

Mehanna, A.S., Maher, T.J., Grongsaard, P.: Design, synthesis and calcium channel blocking activity of diltiazem-verapamil hybrid molecules. Med. Chem. 4(10):704-8, 2014 (DOI:10.4172/2161-0444.1000216).


Editorials
Maher, T.J.: Phenterminees effect on serotonin in plasma? (Letter to the Editor) Am. J. Cardiol. 86: 810-811, 2000.

Current Professional Memberships, Service & Leadership
American Society for Pharmacology and Experimental Therapeutics
International Brain Research Organization/World Federation of Neuroscientists
International Drug Abuse Research Society - Board of Directors
International Society for Amino Acid Research
International Society for Neurochemistry
Rho Chi Honor Society
Phi Lambda Sigma
Sigma Xi
Society for Neuroscience
Society for the Study of Ingestive Behaviors


Personal Interests
Pastoral visitation 
Woodworking
Sports