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Bio

Alok Sharma, PhD
Associate Professor of Pharmaceutical Sciences

Department/Office
School of Pharmacy - 111, Manchester Campus

Contact
alok.sharma@mcphs.edu
(P)603.314.1777


Schools
School of Pharmacy - Worcester/Manchester

Programs
Pharmacy (PharmD)

Education
PhD Northeastern University, Boston, Mass.
MPharm Panjab, University, Chandigarh, India.
BPharm, Birla Institute of Technology, Ranchi, India


Areas of Teaching
Physiology
Pathophysiology
Pharmacology


Scholarly Interests
Signal transduction
Protein-protein interaction
Neuropsychiatric disorders
Dopamine pharmacology


Peer-Reviewed Articles & Book Chapters
Sharma A andCouture J. “A Review of the Pathophysiology, Etiology, and Treatment of Attention-Deficit Hyperactivity Disorder.” Annals of Pharmacotherapy, 48: 209-225, 2014

Sharma A, Bemis M and Desilets AR. “Role of Medium Chain Triglycerides (Axona®) in the Treatment of Mild to Moderate Alzheimer’s Disease.” American Journal of Alzheimer’s Disease and Other Dementias, DOI: 10.1177/1533317513518650, 2014.

Sharma A, Szeto K and Desilets AR. “Efficacy and Safety of Deep Brain Stimulation as an Adjunct to Pharmacotherapy for the Treatment of Parkinson Disease.” The Annals of Pharmacotherapy, 46: 248-254, 2012.

Sharma A and Mayer BJ. “Phosphorylation of p130Cas Initiates Rac Activation and Membrane Ruffling.” BMC Cell Biology, 9: 50, 2008.

Waly M, Olteanu H, Banerjee R, Choi, SW, Mason, JB, Parker, BS, Sukumar S, Shim S, Sharma A, Benzecry JM, Power-Charnitsky VA, Deth RC. Activation of Methionine Synthase by Insulin-Like Growth Factor-1 and Dopamine: A Target for Neurodevelopmental Toxins

Sharma A, Antoku S, Fujiwara K and Mayer BJ. "FIT: A Strategy for Validating the Functional Consequences of Tyrosine Phosphorylation of Specific Substrates in vivo." Molecular and Cellular Proteomics, 2: 1217-1224, 2003.

Sharma A, Waly M and Deth RC. "Protein Kinase C Regulates Dopamine D4 Receptor Mediated Phospholipid Methylation in SK-N-MC Cells." European Journal of Pharmacology, 427: 83-90, 2001.

Zhao R, Chen Y, Tan W, Waly M, Sharma A, Stover P, Rosowsky A, Malewicz B, Deth RC. "Relationship Between Dopamine Stimulated Phospholipid Methylation and the Single Carbon Folate Pathway." Journal of Neurochemistry, 78: 788-796, 2001.

Sharma A, Antoku S and Mayer BJ. "The Functional Interaction Trap: A Novel Strategy to Study Specific Protein-Protein Interactions." In: "Methods in Proteome and Protein Analysis (MPSA 2002), Kamp RM, Calvete J, Choli-Papadopoulou T, eds. Berlin: Springer

Deth RC, Sharma A, Waly M. "Dopamine-Stimulated Solid State Signaling: A Novel Role for Single-Carbon Folates in Human Attention." In: Proceedings of the 12th International Symposium on the Chemistry and Biology of Pteridines and Folates,, Kluwer Academic


Honors
John Neumeyer Research Award (2000)
SmithKline Beecham Pharmacology Award (1997)
Indian Drugs Manufacturing Association Research Award (1993)


Current Professional Memberships, Service & Leadership
American Association of Colleges of Pharmacy
Phi Lambda Sigma, Gamma Gamma Chapter, MCPHS
RHO CHI Honor Society, Beta Tau Chapter, Northeastern University