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Alok Sharma, PhD
Associate Professor of Pharmaceutical Sciences

Department/Office
School of Pharmacy - 111

Contact
alok.sharma@mcphs.edu
(P)603.314.1777


Schools
School of Pharmacy - Worcester/Manchester

Programs
Pharmacy (PharmD)

Education
PhD Northeastern University, Boston, Mass.
MPharm Panjab, University, Chandigarh, India.
BPharm, Birla Institute of Technology, Ranchi, India


Areas of Teaching
Physiology
Pathophysiology
Pharmacology
Introductory Medicinal Chemistry


Scholarly Interests
Signal transduction
Protein-protein interaction
Neuropsychiatric disorders
Dopamine pharmacology


Peer-Reviewed Articles & Book Chapters
Itoh RE, Kurokawa K, Fujioka A, Sharma A, Mayer BJ, Matsuda M. A FRET-Based Probe for Epidermal Growth Factor Receptor Bound Non-Covalently to a Pair of Synthetic Amphipathic Helixes.. Experimental Cell Research, 307: 142-152, 2005.

Waly M, Olteanu H, Banerjee R, Choi, SW, Mason, JB, Parker, BS, Sukumar S, Shim S, Sharma A, Benzecry JM, Power-Charnitsky VA, Deth RC. Activation of Methionine Synthase by Insulin-Like Growth Factor-1 and Dopamine: A Target for Neurodevelopmental Toxins

Sharma A, Antoku S, Fujiwara K and Mayer BJ. "FIT: A Strategy for Validating the Functional Consequences of Tyrosine Phosphorylation of Specific Substrates in vivo." Molecular and Cellular Proteomics, 2: 1217-1224, 2003.

Sharma A, Waly M and Deth RC. "Protein Kinase C Regulates Dopamine D4 Receptor Mediated Phospholipid Methylation in SK-N-MC Cells." European Journal of Pharmacology, 427: 83-90, 2001.

Zhao R, Chen Y, Tan W, Waly M, Sharma A, Stover P, Rosowsky A, Malewicz B, Deth RC. "Relationship Between Dopamine Stimulated Phospholipid Methylation and the Single Carbon Folate Pathway." Journal of Neurochemistry, 78: 788-796, 2001.

Sharma A, Antoku S and Mayer BJ. "The Functional Interaction Trap: A Novel Strategy to Study Specific Protein-Protein Interactions." In: "Methods in Proteome and Protein Analysis (MPSA 2002), Kamp RM, Calvete J, Choli-Papadopoulou T, eds. Berlin: Springer

Deth RC, Sharma A, Waly M. "Dopamine-Stimulated Solid State Signaling: A Novel Role for Single-Carbon Folates in Human Attention." In: Proceedings of the 12th International Symposium on the Chemistry and Biology of Pteridines and Folates,, Kluwer Academic


Honors
John Neumeyer Research Award (2000)

SmithKline Beecham Pharmacology Award (1997)

Indian Drugs Manufacturing Association Research Award (1993)


Current Professional Memberships, Service & Leadership
Phi Lambda Sigma, Gamma Gamma Chapter, MCPHS
RHO CHI Honor Society, Beta Tau Chapter, Northeastern University