Overview
The MS/PhD degree program in Medicinal Chemistry prepares students for a career in scientific research in the areas of drug design, synthetics and biological testing.
Program Highlights
- For students with an undergraduate degree in pharmacy, chemistry, biology or related fields
- Prepares students to design, synthesize and analytically examine drug compounds
- Fall semester start
- Students study how chemical substances behave at a molecular level, and how the chemical properties affect drug kinetics, absorption, distribution, metabolism and excretion
Program Details
Medicinal chemistry is focused on the design, synthesis and biological evaluation of new small molecules as potental therapeutic agents. In addition, medicinal chemistry is concerned with the study of those structural, stereochemical, and physical parameters which affect the biological interaction of synthetic and naturally occurring drugs at the molecular level.
These advanced degrees in medicinal chemistry provide a student with a thorough knowledge of the behavior of chemical substances at the molecular level. Medicinal chemists study the composition of molecules and their interactions in both a chemical and a physical sense, with the aim of predicting the behavior and properties of new substances. They work in the frontier areas of biologically-related scientific research conducted in industrial, governmental and academic laboratories. The work of developing new drugs to treat diseases begins with the medicinal chemist.
Research is directed towards a fuller understanding of the pharmacological actions of such substances leading to improved drug design. Specialization in this program requires a broad knowledge of organic, bio and heterocyclic chemistry, pharmacy, spectroscopic instrumentation, and pharmacology. Ongoing research programs include the synthesis and evaluation of cardiovascular and anticancer drugs.
Minor in Drug Metabolism
Students may elect to complete a minor concentration in drug metabolism, integrating the knowledge of drug metabolism, analysis of pharmaceuticals in biological fluids and incubation mixtures, enzyme kinetics, and animal care and use.
Curriculum
Year I-Fall
COURSE |
TITLE |
SEMESTER HOURS |
CHE 714/714L |
Spectroscopic Analysis |
3 |
CHE 731 |
Advanced Organic Chemistry |
4 |
PSB 710 |
Principles of Pharmaceutical Sciences |
3 |
PSB 818 |
Laboratory Rotations |
0 |
TOTAL |
|
10 |
Year I-Spring
COURSE |
TITLE |
SEMESTER HOURS |
PSB 818 |
Laboratory Rotations |
1 |
PSB 819 |
Graduate Seminar |
1 |
PSB 820 |
Advanced Medicinal Chemistry I |
3 |
PSB 851 |
Biorganic Chemistry |
2 |
|
Elective |
3 |
TOTAL |
|
10 |
Year II-Fall
COURSE |
TITLE |
SEMESTER HOURS |
PSB 810 |
Heterocyclic Chemistry |
2 |
PSB 819 |
Graduate Seminar |
0 |
PSB 880 |
Research |
1 |
|
Elective |
2/3 |
TOTAL |
|
5/6 |
Year II-Spring
COURSE |
TITLE |
SEMESTER HOURS |
PSB 802 |
Chemistry of Macromolecules |
3 |
PSB 819 |
Graduate Seminar |
1 |
PSB 880 |
Research |
1 |
TOTAL |
|
5 |
The PhD* in addition to the MS requirements, will include:
COURSE |
TITLE |
SEMESTER HOURS |
PSB 815 |
Drug Metabolism |
3 |
PSB 819 |
Graduate Seminar |
2 |
PSB 880 |
Research |
3 |
PSB 8XX |
Advanced Medicinal Chemistry II |
3 |
PSB 8XX |
Advanced Topics In Medicinal Chemistry |
3 |
CHE or PSB 700/800 |
Elective |
3 |
PSB 8XX |
Grant Proposal |
3 |
Facilities
Graduate chemistry laboratories are available where advanced students conduct
independent thesis and dissertation experiments and collaborate with faculty on
new research and sponsored grants.
Accreditation
Massachusetts College of Pharmacy and Health Sciences
Massachusetts College of Pharmacy and Health Sciences (MCPHS) is chartered by the Commonwealth of Massachusetts and is authorized to grant undergraduate and graduate degrees in the health sciences and related fields. MCPHS is accredited by the New England Association of Schools and Colleges (NEASC), Inc. through its Commission on Institutions of Higher Education.
Admission Requirements
Many of our programs have different admission requirements and deadlines. To see the specific admission requirements for this program, please click on the link below.
Admission Requirements for Medicinal Chemistry (MS/PhD)
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