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Tewodros Eguale, MD, MS, PhD

Professor of Epidemiology and Biostatistics

Director of Assessment

Department: School of Pharmacy
Office: MATR 4006G

Contact: tewodros.eguale@mcphs.edu
(P) 617.732.2206



Programs

Pharmaceutical Economics and Policy (MS)
Pharmaceutical Economics and Policy (PhD)

Education

Research Associate and Post-doctoral fellow, Brigham Women’s Hospital and Harvard University
PhD, McGill University: Epidemiology, Biostatistics and Occupational Health
MSc, McGill University: Epidemiology, Biostatistics and Occupational Health
MD, Jimma University


Research Interests

Adherence
Adverse Drug Reactions
Compliance
Electronic Health Record
Off-Label Prescribing
Treatment Indications


Peer-Reviewed Articles & Book Chapters

Eguale T, Verma A, Tamblyn R. In Defense of Off-label Prescribing-Reply. JAMA Intern Med. 2016 Jun 1; 176(6):861-2. PMID: 27273486.

Winslade N, Eguale T, Tamblyn R. Optimising the changing role of the community pharmacist: a randomised trial of the impact of audit and feedback. BMJ Open. 2016; 6(5):e010865. PMID: 27207626.

Tamblyn R, Girard N, Dixon WG, Haas J, Bates DW, Sheppard T, Eguale T, Buckeridge D, Abrahamowicz M, Forster A. Pharmacosurveillance without borders: electronic health records in different countries can be used to address important methodological issues in estimating the risk of adverse events. J Clin Epidemiol. 2016 May 20. PMID: 27212138.

Wong J, Motulsky A, Eguale T, Buckeridge DL, Abrahamowicz M, Tamblyn R. Treatment Indications for Antidepressants Prescribed in Primary Care in Quebec, Canada, 2006-2015. JAMA. 2016 May 24-31; 315(20):2230-2. PMID: 27218634.

Slight SP, Beeler PE, Seger DL, Amato MG, Her QL, Swerdloff M, Dalleur O, Nanji KC, Cho I, Maniam N, Eguale T, Fiskio JM, Dykes PC, Bates DW. A cross-sectional observational study of high override rates of drug allergy alerts in inpatient and outpatient settings, and opportunities for improvement. BMJ Qual Saf. 2016 Mar 18. PMID: 26993641.

Eguale T, Buckeridge DL, Verma A, Winslade NE, Benedetti A, Hanley JA, Tamblyn R. Association of Off-label Drug Use and Adverse Drug Events in an Adult Population. JAMA Intern Med. 2016 Jan; 176(1):55-63. PMID: 26523731.

Slight SP, Eguale T, Amato MG, Seger AC, Whitney DL, Bates DW, Schiff GD. The vulnerabilities of computerized physician order entry systems: a qualitative study. J Am Med Inform Assoc. 2016 Mar; 23(2):311-6. PMID: 26568606.

Alqahtani S, Seoane-Vazquez E, Rodriguez-Monguio R, Eguale T. Priority review drugs approved by the FDA and the EMA: time for international regulatory harmonization of pharmaceuticals? Pharmacoepidemiol Drug Saf. 2015 Jul; 24(7):709-15. PMID: 26013294.

Tian Z, Sun S, Eguale T, Rochefort CM. Automated Extraction of VTE Events From Narrative Radiology Reports in Electronic Health Records: A Validation Study. Med Care. 2015 Apr 28. PMID: 25924079.

Tamblyn R, Ernst P, Winslade N, Huang A, Grad R, Platt RW, Ahmed S, Moraga T, Eguale T. Evaluating the impact of an integrated computer-based decision support with person-centered analytics for the management of asthma in primary care: a randomized controlled trial. J Am Med Inform Assoc. 2015 Jul; 22(4):773-83. PMID: 25670755; PMCID: PMC4482273 [Available on 07/01/16].

Schiff GD, Amato MG, Eguale T, Boehne JJ, Wright A, Koppel R, Rashidee AH, Elson RB, Whitney DL, Thach TT, Bates DW, Seger AC. Computerised physician order entry-related medication errors: analysis of reported errors and vulnerability testing of current systems. BMJ Qual Saf. 2015 Apr; 24(4):264-71. PMID: 25595599; PMCID: PMC4392214.

Rochefort CM, Verma AD, Eguale T, Lee TC, Buckeridge DL. A novel method of adverse event detection can accurately identify venous thromboembolisms (VTEs) from narrative electronic health record data. J Am Med Inform Assoc. 2015 Jan; 22(1):155-65. PMID: 25332356; PMCID: PMC4433368 [Available on 01/01/16].

Tamblyn R, Eguale T, Huang A, Winslade N, Doran P. The incidence and determinants of primary nonadherence with prescribed medication in primary care: a cohort study. Ann Intern Med. 2014 Apr 1; 160(7):441-50. PMID: 24687067.

Krotneva SP, Ramjaun A, Reidel KE, Eguale T, Trabulsi N, Mayo N, Tamblyn R, Meguerditchian AN. Use of hormonal therapy in senior breast cancer patients treated with or without radiotherapy. Curr Oncol. 2014 Feb; 21(1):e105-15. PMID: 24523607; PMCID: PMC3921034.

Wang TY, Eguale T, Tamblyn R. Guidelines adherence in the treatment of patients with newly diagnosed type 2 diabetes: a historical cohort comparing the use of metformin in Quebec pre and post-Canadian Diabetes Association guidelines. BMC Health Serv Res. 2013 Oct 25; 13:442. PMID: 24160916; PMCID: PMC4231333.

Forster AJ, Auger C. Using information technology to improve the monitoring of outpatient prescribing. JAMA Intern Med. 2013 Mar 11; 173(5):382-4. PMID: 23381469.

Tamblyn R, Huang AR, Meguerditchian AN, Winslade NE, Rochefort C, Forster A, Eguale T, Buckeridge D, Jacques A, Naicker K, Reidel KE. Using novel Canadian resources to improve medication reconciliation at discharge: study protocol for a randomized controlled trial. Trials. 2012; 13:150. PMID: 22920446; PMCID: PMC3502593.

Meguerditchian AN, Dauphinee D, Girard N, Eguale T, Riedel K, Jacques A, Meterissian S, Buckeridge DL, Abrahamowicz M, Tamblyn R. Do physician communication skills influence screening mammography utilization? BMC Health Serv Res. 2012 Jul 25; 12:219. PMID: 22831648; PMCID: PMC3422198.

Eguale T, Buckeridge DL, Winslade NE, Benedetti A, Hanley JA, Tamblyn R. Drug, patient, and physician characteristics associated with off-label prescribing in primary care. Arch Intern Med. 2012 May 28; 172(10):781-8. PMID: 22507695.

Huang AR, Mallet L, Rochefort CM, Eguale T, Buckeridge DL, Tamblyn R. Medication-related falls in the elderly: causative factors and preventive strategies. Drugs Aging. 2012 May 1; 29(5):359-76. PMID: 22550966.

Kennie-Kaulbach N, Farrell B, Ward N, Johnston S, Gubbels A, Eguale T, Dolovich L, Jorgenson D, Waite N, Winslade N. Pharmacist provision of primary health care: a modified Delphi validation of pharmacists' competencies. BMC Fam Pract. 2012; 13:27. PMID: 22455482; PMCID: PMC3372430.

Tamblyn R, Eguale T, Buckeridge DL, Huang A, Hanley J, Reidel K, Shi S, Winslade N. The effectiveness of a new generation of computerized drug alerts in reducing the risk of injury from drug side effects: a cluster randomized trial. J Am Med Inform Assoc. 2012 Jul-Aug; 19(4):635-43. PMID: 22246963; PMCID: PMC3384117.

Eguale T, Winslade N, Hanley JA, Buckeridge DL, Tamblyn R. Enhancing pharmacosurveillance with systematic collection of treatment indication in electronic prescribing: a validation study in Canada. Drug Saf. 2010 Jul 1; 33(7):559-67. PMID: 20553057.

Tamblyn R, Abrahamowicz M, Dauphinee D, Wenghofer E, Jacques A, Klass D, Smee S, Eguale T, Winslade N, Girard N, Bartman I, Buckeridge DL, Hanley JA. Influence of physicians' management and communication ability on patients' persistence with antihypertensive medication. Arch Intern Med. 2010 Jun 28; 170(12):1064-72. PMID: 20585073.

Eguale T, Tamblyn R, Winslade N, Buckeridge D. Detection of adverse drug events and other treatment outcomes using an electronic prescribing system. Drug Saf. 2008; 31(11):1005-16. PMID: 18840020.

Malik S, Greenwood CM, Eguale T, Kifle A, Beyene J, Habte A, Tadesse A, Gebrexabher H, Britton S, Schurr E. Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia. Hum Genet. 2006 Feb; 118(6):752-9. PMID: 16292672.

Eguale T, Bartlett G, Tamblyn R. Rare visible disorders/ diseases as individually identifiable health information. AMIA Annu Symp Proc. 2005; 947. PMID: 16779234; PMCID: PMC1560775.

Gebre-Selassie S, Eguale T, Abebe G, Medhin G. Disease-related knowledge and practices of tuberculosis patients. Ethiop J Health Sci. 2003; 3(13):77-80.

Doherty TM, Demissie A, Olobo J, Wolday D, Britton S, Eguale T, Ravn P, Andersen P. Immune responses to the Mycobacterium tuberculosis-specific antigen ESAT-6 signal subclinical infection among contacts of tuberculosis patients. J Clin Microbiol. 2002 Feb; 40(2):704-6. PMID: 11826002; PMCID: PMC153355.

Eguale, T., Abate, G. and Balcha, F. Relapsing fever in Hossana, Ethiopia: a clinical and epidemiological study. Ethiop J Health Sci. 2002; 2(12):103-108.

Olobo JO, Geletu M, Demissie A, Eguale T, Hiwot K, Aderaye G, Britton S. Circulating TNF-alpha, TGF-beta, and IL-10 in tuberculosis patients and healthy contacts. Scand J Immunol. 2001 Jan; 53(1):85-91. PMID: 11169211.

Demissie A, Ravn P, Olobo J, Doherty TM, Eguale T, Geletu M, Hailu W, Andersen P, Britton S. T-cell recognition of Mycobacterium tuberculosis culture filtrate fractions in tuberculosis patients and their household contacts. Infect Immun. 1999 Nov; 67(11):5967-71. PMID: 10531255; PMCID: PMC96981.

Ravn P, Demissie A, Eguale T, Wondwosson H, Lein D, Amoudy HA, Mustafa AS, Jensen AK, Holm A, Rosenkrands I, Oftung F, Olobo J, von Reyn F, Andersen P. Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis. J Infect Dis. 1999 Mar; 179(3):637-45. PMID: 9952370.