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Preventing or Being Overprotective? Aspirin and Statin Use for Primary Prevention in Older Adults

For decades, aspirin and statin therapy has been widely administered for atherosclerotic cardiovascular disease (ASCVD) prevention. The older adult population has the highest absolute risk for ASCVD and may likely be on both agents for primary prevention. For the use of aspirin in primary prevention of ASCVD in older adults, there has been practice-changing primary literature findings. To reflect the uncertain benefit of aspirin in older adults, the 2019 American College of Cardiology (ACC) and the American Heart Association (AHA) updated the primary prevention of cardiovascular disease guideline. Much remains in question with respect to statin therapy in older adults for primary prevention of ASCVD. This module will include review of two ongoing large trials that address the lack of strong evidence to clinically guide statins’ appropriateness in older adults for primary CV prevention.

Learning Objectives

Upon completion of this activity, the participant should be able to:

  • Recall the most recent guideline recommendations for use of aspirin or statins in primary prevention of ASCVD in older adults.
  • Discuss the findings from primary literature that could lead to changes in practice for both aspirin and statins in older adults for primary prevention of ASCVD.


Jasmine (Sea Yean) An, PharmD is a PGY1 pharmacy resident at Baystate Medical Center in Springfield, MA. She received her Doctor of Pharmacy from Northeastern University - Bouvé College of Health Sciences in 2020. Her current area of interest is in geriatrics and internal medicine.

Free to MCPHS Alumni and full-time employees; $12.00 for all other professionals.


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Release Date: June 8, 2021
Expiration Date: June 8, 2022
Contact Hours: 1 (.10 CEU)
Universal Activity Number: 0026-0000-21-133-H01-P | Knowledge-based
ACPE Topic Designator: Drug Therapy


Massachusetts College of Pharmacy and Health Sciences is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Massachusetts College of Pharmacy and Health Sciences designates this educational activity for a total of 1 contact hours (0.1 CEUs).

Requirements for Credit

In order to receive credit, the participant must view the entire presentation and complete the pre and post-test, and evaluation. Upon completion participant credit will be reported to CPE Monitor. Transcripts may be printed from CPE Monitor.

Statement of Disclosure

It is the policy of MCPHS-CE to ensure balance, independence, objectivity and scientific rigor in all of its educational activities. All individuals engaged in the planning of a continuing education activity and who are in a position to control the educational content are required to disclose any financial relationships with ineligible companies occurring within the past 24 months. The intent of this policy is to identify and mitigate any potential conflict of interest that may directly or indirectly affect the activity. All recommendations involving clinical medicine must be based on evidence accepted within the medical profession.

MCPHS will identify, review and mitigate all conflicts of interest that speakers, authors or planners disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation.

No funding from industry provided for this event. No exhibitors will be present.
Jasmine (Sea Yean) An and MCPHS CE staff members hold no financial relationships with ineligible companies, related to the content of this presentation.