Guang Yan, PhD
Associate Professor of Pharmaceutical Sciences
School
School of Pharmacy
Department
Pharmaceutical Sciences
Office Location
19 Foster 508
Worcester
Office Phone Office Phone: 508.373.5856
About
Dr. Guang Yan joined the School of Pharmacy at MCPHS in 2015. He teaches Pharmaceutics II and its laboratory, as well as courses in cosmeceuticals and skin care products. He also teaches advanced pharmaceutics courses to graduate students, including Advanced Physical Pharmacy and Novel Drug Delivery.
Dr. Yan earned his PhD in Pharmaceutics from the University of Utah. Prior to joining MCPHS, he served as an assistant professor at Idaho State University and worked as a research scientist in the pharmaceutical industry. His work focuses on pharmaceutical formulation and drug delivery systems.
Education
- PhD, Pharmaceutics, University of Utah
Research Interests
- Transdermal drug delivery (microneedles, iontophoresis, prodrugs and formulation development).
- Controlled and targeted drug delivery (microparticles and nanoparticles).
Featured Affiliations
American Associate of College of Pharmacy (AACP)
WebsiteAmerican Association of Pharmaceutical Scientists (AAPS)
WebsiteEducation
- PhD, Pharmaceutics, University of Utah
Research Interests
- Transdermal drug delivery (microneedles, iontophoresis, prodrugs and formulation development).
- Controlled and targeted drug delivery (microparticles and nanoparticles).
Publications
- Lobo S, Yan G*, Evaluation iontophoretic delivery of a cationic ketoprofen prodrug for treating nociceptive symptoms in monosodium iodoacetate induced osteoarthritic rat model. Int J Pharm. 569: 118598 (2019).
- Lobo S, Yan G*, Improving the direct penetration into tissues underneath the skin with iontophoresis delivery of a ketoprofen cationic prodrug. Int J Pharm. 535: 228 -236 (2018).
- Yan G*, Arelly N, Farhan N, Lobo S, Li H, Enhancing DNA delivery into the skin with a motorized microneedle device. Eur J Pharm Sci. 52: 215-22 (2014).
- Yan G*, Lobo S, Li H, Can diclofenac ester prodrug promotes direct penetration across the skin? J Chem Pharm Res. 6(7): 2701-2713 (2014).
- Lobo S, Farhan N, Li H, Yan G*. Evaluation of diclofenac prodrugs for enhancing transdermal delivery. Drug Dev Ind Pharm. 40(3): 425-432 (2014).
- Yan G*, Moribe K, Otsuka M, Papangkorn K, Higuchi WI. Quantitative determination of lattice fluoride effects on the solubility and crystallinity of carbonated apatites with incorporated fluoride. Caries Research. 47 (3):193–202 (2013).
- Ding D, Yan G*. A Convenient Method for the Synthesis of Aminomethyl-monoalkyl-phosphinate. Chin J Chem, 30: 1906-1908 (2012).
- Yan G*, Warner KS, Zhang J, Sharma S, Gale BK. Evaluation needle length and density of microneedle arrays in the pretreatment of skin for transdermal drug delivery. Int J Pharm, 391(1-2):7-12 (2010).
- Yan G, Xu Q, Anissimov YG, Hao J, Higuchi WI, Li SK*. Alternating current (AC) iontophoretic transport across human epidermal membrane: effects of AC frequency and amplitude. Pharm Res, 25(3): 616-624 (2008).
- Papangkorn K, Yan G, Heslop D, Moribe K, Baig AA, Otsuka M, Higuchi WI*. Influence of crystallite microstrain on surface complexes governing the metastable equilibrium solubility behavior of carbonated apatites. J Colloid Interface Sci, 320(1):96-109 (2008).
- Longo N*, Li SK, Yan G, Kochambilli RP, Papangkorn K, Berglund D, Ghanem AH, Ashurst CL, Ernst SL, Pasquali M, Higuchi WI. Noninvasive iontophoretic phenylalanine monitoring in patients with phenylketonuria. J Inherit Metab Dis, 30: 910-915 (2007).
- Yan G, Li SK, Higuchi WI*. Evaluation the constant alternating current iontophoresis for transdermal drug delivery. J Control Release, 110(1): 141-50 (2005).
- Yan G, Li SK, Peck KD, Zhu H, Higuchi WI*. Effects of electrophoresis and electroosmosis during alternating current iontophoresis across human epidermal membranes. J Pharm Sci, 94(3): 547-558 (2005).
- Yan G*, Li SK, Peck KD, Zhu H, Higuchi WI. Quantitatively study of electrophoretic and electroosmotic enhancement during alternating current iontophoresis across synthetic membranes. J Pharm Sci, 93(12): 2895-908 (2004).
- Yan G, Higuchi WI, Szabo A, Li SK*. Correlation of transdermal iontophoretic phenylalanine and mannitol transport: test of the internal standard concept under DC iontophoresis and constant resistance AC iontophoresis. J Control Release, 98(1): 127-38 (2004).
- Zhu H, Peck KD, Miller DJ, Liddell MR, Yan G, Higuchi WI, Li SK*. Investigation of properties of human epidermal membrane under constant conductance alternating current iontophoresis. J Control Release. 89(1): 31-46 (2003).
- Li H, Yan G, Kern SE, and Lim CS*. Correlation among agonist dose, rate of import, and transcriptional activity of liganded progesterone receptor B isoform in living cells, Pharm Res. 20(10) 1574-80 (2003).
- Yan G*, Li H, Zhang R, Ding D. Preparation and evaluation of a sustained-release formulation of nifedipine HPMC tablets. Drug Dev Ind Pharm. 26(6): 681-6 (2000).
Honors and Awards
- MCPHS (W/M) Department of Pharmaceutical Sciences Academic of the Year for Excellence in Teaching, Research and Service (2018-2019)