School
School of Pharmacy
Department
Pharmaceutical Sciences
Office Location
White 314
Boston
Office Phone Office Phone: 617.274.3389
Website Website: Google Scholar
About
Dr. Devyani Joshi is an Assistant Professor of Pharmaceutics at MCPHS, where she integrates her multidisciplinary training in pharmaceutics, immunology, and drug delivery sciences to advance the development of biologics and vaccines.
Her research focuses on the formulation and delivery of monoclonal antibodies and infectious disease vaccines, with an emphasis on the interplay between formulation science and immune-based therapeutics to enhance the safety, efficacy, and global accessibility of biologic medicines. She applies mechanistic, analytical, and translational approaches to develop formulations suited for real-world challenges such as temperature instability, aggregation risk, and variable supply chain conditions.
Education
- PhD in Pharmaceutical Sciences, Mercer University
- BPharm, University of Mumbai
- Postgraduate Training:
- Postdoctoral Fellowship, Emory University
- ORISE Fellowship, Centers for Disease Control and Prevention (CDC)
Research Interests
- Infectious disease vaccines
- Adjuvant systems
- Particulate, lipid-based, and polymeric delivery platforms
- Micro- and naoparticles, transdermal, nasal, oral vaccine delivery systems
- In-vitro and in-vivo vaccine evaluation
Featured Affiliations
American Association of Pharmaceutical Scientists
WebsiteAmerican Association of Immunologists
WebsiteEducation
- PhD in Pharmaceutical Sciences, Mercer University
- BPharm, University of Mumbai
- Postgraduate Training:
- Postdoctoral Fellowship, Emory University
- ORISE Fellowship, Centers for Disease Control and Prevention (CDC)
Research Interests
- Infectious disease vaccines
- Adjuvant systems
- Particulate, lipid-based, and polymeric delivery platforms
- Micro- and naoparticles, transdermal, nasal, oral vaccine delivery systems
- In-vitro and in-vivo vaccine evaluation
Publications
Peer-reviewed Publications:
- Kumar, S., Jain, S., Wali, B., Zarnitsyna, V. I., Joshi, D., Ellis, M. L., ... & Suthar, M. S. (2025). The XBB. 1.5 COVID-19 vaccine elicits a durable antibody response to ancestral and XBB. 1.5 SARS-CoV-2 spike proteins. Science Translational Medicine, 17(814), eadu8067.
- Zhong, Z., Quiñones-Pérez, M., Dai, Z., Juarez, V. M., Bhatia, E., Carlson, C. R., ... Joshi. D.J., …. & Singh, A. (2025). Human immune organoids to decode B cell response in healthy donors and patients with lymphoma. Nature Materials, 24(2), 297-311.
- Sumner, K. M., Yadav, R., Noble, E. K., Sandford, R., Joshi, D., Tartof, S. Y., ... & Flannery, B. (2024). Anti–SARS-CoV-2 antibody levels associated with COVID-19 protection in outpatients tested for SARS-CoV-2, US flu vaccine effectiveness network, October 2021–June 2022. The Journal of infectious diseases, 230(1), 45-54.
- Sandford, R., Yadav, R., Noble, E. K., Sumner, K., Joshi, D., Tartof, S. Y., ... & Rogier, E. (2024). Antibody Response to Symptomatic Infection With SARS‐CoV‐2 Omicron Variant Viruses, December 2021–June 2022. Influenza and Other Respiratory Viruses, 18(7), e13339.
- Joshi, D., Shah, S., Chbib, C., & Uddin, M. N. (2024). Potential of DPD ((S)-4, 5-dihydroxy-2, 3-pentanedione) Analogs in Microparticulate Formulation as Vaccine Adjuvants. Pharmaceuticals, 17(2), 184.
- Wimmers, F., Burrell, A. R., Feng, Y., Zheng, H., Arunachalam, P. S., Hu, M., Spranger, S., Nyhoff, L. E., Joshi, D., ... & Pulendran, B. (2023). Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth. Cell.
- Joshi, D., Nyhoff, L. E., Zarnitsyna, V. I., Moreno, A., Manning, K., Linderman, S., ... & Wrammert, J. (2023). Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults. iScience.
- Shah, S. M., Joshi, D., Chbib, C., Roni, M. A., & Uddin, M. N. (2023). The Autoinducer N-Octanoyl-L-Homoserine Lactone (C8-HSL) as a Potential Adjuvant in Vaccine Formulations. Pharmaceuticals, 16(5), 713.
- Kale, A., Joshi, D., Menon, I., Bagwe, P., Patil, S., Vijayanand, S., ... & D’Souza, M. J. (2023). Zika Vaccine Microparticles (MPs)-Loaded Dissolving Microneedles (MNs) Elicit a Significant Immune Response in a Pre-Clinical Murine Model. Vaccines, 11(3), 583.
- Patil, S., Vijayanand, S., Joshi, D., Menon, I., Gomes, K. B., Kale, A., ... & D'Souza, M. J. (2023). Subunit microparticulate vaccine delivery using microneedles trigger significant SARS-spike-specific humoral and cellular responses in a preclinical murine model. International Journal of Pharmaceutics, 632, 122583.
- Gupta, S. L., Mantus, G., Manning, K. E., Ellis, M., Patel, M., Ciric, C. R., Lu, A., Turner, J. S., O’Halloran, J. A., Presti, R. M., Joshi, D. J., ... & Wrammert, J. (2022). Loss of Pfizer (BNT162b2) vaccine-induced antibody responses against the SARS-CoV-2 Omicron variant in adolescents and adults. Journal of virology, 96(17), e00582-22.
- Vijayanand, S., Patil, S., Joshi, D., Menon, I., Braz Gomes, K., Kale, A., ... & D’Souza, M. J. (2022). Microneedle Delivery of an Adjuvanted Microparticulate Vaccine Induces High Antibody Levels in Mice Vaccinated against Coronavirus. Vaccines, 10(9), 1491.
- Kale, A., Joshi, D., Menon, I., Bagwe, P., Patil, S., Vijayanand, S., ... & D'Souza, M. (2022). Novel microparticulate Zika vaccine induces a significant immune response in a preclinical murine model after intramuscular administration. International Journal of Pharmaceutics, 624, 121975.
- Joshi, D., Gala, R. P., Uddin, M. N., & D'Souza, M. J. (2021). Novel ablative laser mediated transdermal immunization for microparticulate measles vaccine. International Journal of Pharmaceutics, 606, 120882.
- Joshi, D., Chbib, C., Uddin, M. N., & D’Souza, M. J. (2021). Evaluation of microparticulate (S)-4, 5-dihydroxy-2, 3-pentanedione (DPD) as a potential vaccine adjuvant. The AAPS Journal, 23(4), 84.
- Joshi, D. J., Chitre, N. M., Bansal, A., Murnane, K. S., & D’Souza, M. J. (2021). Formulation and characterization of microcapsules encapsulating PC12 cells as a prospective treatment approach for Parkinson’s disease. AAPS PharmSciTech, 22(4), 149.
- Joshi, D., Uddin, M. N., D’Souza, M. J., & Gala, R. P. (2021). Technology Update: Laser Ablation Technology for Transdermal Immunization. J Vaccines Vaccin. S, 15.
Book Chapters:
- Gala, R. P., Bajaj, L., Bansal, A., Gomes, K. B., Joshi, D., Menon, I., ... & D’Souza, M. J. (2020). Oral vaccine delivery: the coming age of particulate vaccines to elicit mucosal immunity. In Mucosal Delivery of Drugs and Biologics in Nanoparticles (pp. 155-175). Springer, Cham.
- Sarthak, S., Dedeepya, P., Emmanuel, A., Amit, B., Devyani, J., Smital, P., ... & D'Souza, M. J. (2024). Vaccine adjuvants and carriers. In Advanced Vaccination Technologies for Infectious and Chronic Diseases (pp. 13-36). Academic Press.
Honors and Awards
- Best abstract award by AAPS for abstract “Novel 3D Printing Technology for Formulation of Oral Dissolving Films (ODFs)”. AAPS PharmSci360 conference, 2020
- Best abstract award by AAPS for abstract “Crafting Immunity: Novel Microparticulate Measles Vaccine for Needle-free Transdermal Immunization”. Awarded a complimentary registration to AAPS 2020 meeting supported by AstraZeneca. AAPS PharmSci360.
- First Place in Poster Presentation for the poster “Treatment of Parkinson's Disease using Cell-based therapy”. Mercer Annual COP Research Day, 2020
- Second place in poster presentation for the poster “Measles vaccination via 3D printed Oral Dissolving Films (ODFs)” in the pharmaceutical category at NanoFlorida 2020, Biomedical Nanotechnology Conference