Iman Zaghloul, PhD
Professor of Pharmaceutics
School
School of Pharmacy
Department
Pharmaceutical Sciences
Office Location
White 314
Boston
Office Phone Office Phone: 617.732.2757
About
Dr. Iman Zaghloul is a pharmaceutical scientist with expertise in pharmacokinetics and biopharmaceutics. She earned her doctorate in Pharmacokinetics and Biopharmaceutics from the University of Pittsburgh School of Pharmacy, where her research focused on immunosuppressant therapies in transplant animal models.
Following her doctoral training, she worked in industry conducting preclinical pharmacokinetic research before transitioning to academia. She later served as an assistant professor and Chair of the Department of Clinical Pharmacy at King Saud University in Riyadh. After returning to the United States, she joined MCPHS as a faculty member and became a full professor in Pharmaceutics in 2020. Dr. Zaghloul has mentored numerous graduate students and contributed to collaborative research initiatives across the university.
Education
- Postdoctoral Research Associate, American Cyanamid Company
- Doctorate in Biopharmaceutics and Pharmacokinetics, University of Pittsburgh School of Pharmacy
- Bachelor of Science with Honors, University of Alexandria College of Pharmacy
Research Interests
- Preclinical pharmacokinetics of drugs in disease animal model.
- Allometric scaling, toxico-kinetics and Pharmacodynamics
- Drug disposition of new biotherapeutic and small-molecule entities
Programs
- Clinical Investigation and Development (MS)
- Clinical Research (MS)
- Medicinal Chemistry (MS)
- Medicinal Chemistry (PhD)
- Pharmaceutical Business (BS)
- Pharmaceutical Sciences (BS)
- Pharmaceutics (MS)
- Pharmaceutics (PhD)
- Pharmacology & Toxicology (BS)
- Pharmacology (MS)
- Pharmacology (PhD)
- Pharmacy (PharmD)—Direct Entry
- Pharmacy (PharmD)—Non-Traditional Pathway
- Regulatory Affairs & Health Policy (MS)
- Regulatory Sciences (MS)
- Clinical Research Graduate Certificate
- Health Policy Graduate Certificate
- Regulatory Affairs Graduate Certificate
Featured Affiliations
American Association of Pharmaceutical Scientist (AAPS)
WebsiteAmerican Association of Colleges of Pharmacy (AACP)
WebsiteMember of the Advisory Board of the Saudi Pharmaceutical Journal
Education
- Postdoctoral Research Associate, American Cyanamid Company
- Doctorate in Biopharmaceutics and Pharmacokinetics, University of Pittsburgh School of Pharmacy
- Bachelor of Science with Honors, University of Alexandria College of Pharmacy
Research Interests
- Preclinical pharmacokinetics of drugs in disease animal model.
- Allometric scaling, toxico-kinetics and Pharmacodynamics
- Drug disposition of new biotherapeutic and small-molecule entities
Programs
- Clinical Investigation and Development (MS)
- Clinical Research (MS)
- Medicinal Chemistry (MS)
- Medicinal Chemistry (PhD)
- Pharmaceutical Business (BS)
- Pharmaceutical Sciences (BS)
- Pharmaceutics (MS)
- Pharmaceutics (PhD)
- Pharmacology & Toxicology (BS)
- Pharmacology (MS)
- Pharmacology (PhD)
- Pharmacy (PharmD)—Direct Entry
- Pharmacy (PharmD)—Non-Traditional Pathway
- Regulatory Affairs & Health Policy (MS)
- Regulatory Sciences (MS)
- Clinical Research Graduate Certificate
- Health Policy Graduate Certificate
- Regulatory Affairs Graduate Certificate
Publications
- Elshafie S, Villa Zapata L, Tackett RL, Zaghloul IY, Young HN. Cardiovascular and Metabolic Adverse Events of Endocrine Therapies in Women with Breast Cancer: A Disproportionality Analysis of Reports in the FDA Adverse Event Reporting System. Cancer Medicine. 2025;14(1): e70548. doi:10.1002/cam4.70548
- Elshafie S, Trivedi R, Villa Zapata LA, Tackett RL, Zaghloul IY, Young HN. Adherence, clinical benefits and adverse effects of endocrine therapies among women with nonmetastatic breast cancer in developing countries: a systematic review and meta‐analysis. Cancer. 2024;1‐21. doi:10.1002/cncr.35550
- Steven Crosby, Maria D. Kostka-Rokosz, Gerard D'Souza, Paul Kiritsy, Yulia Murray, Anand Sridhar, Iman Zaghloul, Stephen Kerr. Innovative Models to Increase Student Retention and Remediation in the Doctor of Pharmacy Curriculum, American Journal of Pharmaceutical Education, Volume 87, Issue 8, 2023, 100459, ISSN 0002-9459,
- Zaghloul IY, Bedenice D, Ceresia ML, Jones PH, Sanchez-Londono A, Lobo MN, Böhlke M, Paradis MR. Comparative pharmacokinetics of phenylbutazone in healthy young-adult and geriatric horses. Am J Vet Res. 2024 Jun 28;85(8): ajvr.24.01.0012. doi: 10.2460/ajvr.24.01.0012. PMID: 38942059.
- Pauli JR, Muñoz VR, Vieira RFL, Nakandakari SCBR, Macêdo APA, de Lima RD, Antunes GC, Simabuco FM, da Silva ASR, de Moura LP, Ropelle ER, Cintra DE, Mekary RA, Zaghloul I. (2023). Exercise training restores weight gain and attenuates hepatic inflammation in a rat model of non-celiac gluten sensitivity. J Cell Biochem. 124(4):520-532. doi: 10.1002/jcb.30387. Epub 2023 Feb 15. PMID: 36791261.
- Jillian Minuto, Daniela Bedenice, Michelle Ceresia1, Iman Zaghloul, Mark Böhlke3 and Melissa R. Mazan. Clinical effects and pharmacokinetics of nebulized lidocaine in healthy horses. Front. Vet. Sci., 2022; 15. https://doi.org/10.3389/fvets.2022.984108
- Srivastava, K., Patel, N., Tabbara, M., Liew, A., Zaghloul, I., Migliore, M. M., & Mekary, R. A. (2021). Thromboembolism, Bleeding, and Mortality Incidence of Direct Oral Anticoagulants Versus Warfarin Postbariatric Surgery. The American journal of medicine, 134(11), 1403–1412.e2. https://doi.org/10.1016/j.amjmed.2021.06.021.
- Walaa Albenayan, Nabil Alruwaili, José Rodrigo Pauli, Andrella King, Mattia Migliore, and Iman Zaghloul. Development and Validation of a Gliadin Induced Intestinal Enteropathy Rat Model of Non-Celiac Gluten Sensitivity. J Pharm Pharmacol Res 2021; 5 (4): 205-217. DOI: 10.26502/fjppr.045.
- Vieira RFL, Muñoz VR, Junqueira RL, de Oliveira F, Gaspar RC, Nakandakari SCBR, Costa SO, Torsoni MA, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Zaghloul I, Mekary RA, Pauli JR. Time-restricted feeding combined with aerobic exercise training can prevent weight gain and improve metabolic disorders in mice fed a high-fat diet. J Physiol. 2021 Jan 15. doi: 10.1113/JP280820. Online ahead of print. PMID: 33450053.
- Lak AM, Lamba N, Pompilus F, Yunusa I, King A, Sultan I, Amamoo J, Al-Otaibi NM, Alasmari M, Zaghloul I, Aglio L, Cerecedo-Lopez CD, Tafel I, Smith TR, Mekary RA, Zaidi H. Minimally invasive versus open surgery for the correction of adult degenerative scoliosis: a systematic review. Neurosurg Rev. 2021 Apr;44 (2):659-668. doi: 10.1007/s10143-020-01280-9. Epub 2020 Mar 12. PMID: 32166508.
- Gaspar RC, Muñoz VR, Nakandakari SCBR, Vieira RFL, da Conceição LR, de Oliveira F, Crisol BM, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Zaghloul I, Mekary RA, Pauli JR. Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats. Exp Gerontol. 2020 Oct 1;139:111021. doi: 10.1016/j.exger.2020.111021. Epub 2020 Jul 10. PMID: 32659331.
- Hurtig M, Zaghoul I, Sheardown H, Schmidt T, Liu L, Zhang L, Elsaid K, Jay GD (2018). Two Compartment Pharmacokinetic Model Describes the Intra-Articular Delivery and Retention of rhPRG4 Following ACL Transection in the Yucatan Mini Pig, J of Ortho Res 2018; 37:386–396, 2019.
- Altuwaijri N, Cote D, Lamba N, Albenayan W, Ren S, Zaghloul I, Doucette J, Zaidi H, Rania Mekary and Timothy Smith. Headache Resolution after Rathke Cleft Cyst Resection: a Meta-Analysis. World Neurosurgery 2018; vol 111, e764-772.
- Elshafie S, Roberti AM, Zaghloul I. Pharmacovigilance in developing countries (Part II): A path forward; Int J Clin Pharm 2018; ISSN 2210-7703; DOI 10.1007/s11096-017-0588-2.
- Elshafie S, Zaghloul I, Roberti AM. Pharmacovigilance in developing countries (Part I): Importance and Challenges; Int J Clin Pharm 2017; ISSN 2210-7703; DOI 10.1007/s11096-017-0570-z.
Honors and Awards
- Dean''s Service Award 2025
- MCPHS Service Award (Pharm. Sci. Dept) 2021 - 2022
- Officer, Phi Kappa Phi Honor Society 2016 - present
- Member, Rho Chi (Alpha Omicron Chapter) Pharmacy Honor Society 1986 - present
- AAPS Abstract Reviewer 2017-2019
- Certificate of Appreciation, Awarded at the 5th Annual Graduate Student Meeting (GRASP), Rutgers Graduate Assistantship, School of Pharmacy, University of Pittsburgh 1982-1987
- Outstanding Student of the Year, College of Pharmacy, University of Alexandria