Skip to content

Updated Guidance for the Pharmacological Treatment of Clostridium Difficile Infections

This CE will provide pharmacists updated guidelines and best practices for treating Clostridium Dificile Infections (CDI). The updated guidance takes into account data that has emerged to support the use of new treatments in the management of CDI. The latest instructions will introduce pharmacists to up to date protocols for the initial treatment, recurrent episodes, as well as new recommendations for adjunctive treatment in CDI.

Learning Objectives

Upon completion of this activity, the participant will be able to:

  • Use the 2021 IDSA/SHEA guidelines and emerging clinical evidence to improve current practice in the treatment of CDI.
  • Explain the place in therapy of bezlotoxumab for the management of CDI.
  • Compare characteristics of various pharmacologic treatment options for the management of CDI.


Shane J. Softy, B.S., PharmD., is a current PGY-1 acute-care pharmacy resident at Mount Auburn Hospital as part of the Beth Israel Lahey Health System. He has received a Bachelor of Science degree from Virginia Polytechnic Institute and State University with a major in Animal and Poultry Sciences and a minor in Chemistry and Psychology. He went on to receive his Doctorate-of-Pharmacy from Virginia Commonwealth University.

Residency Mentor: Oussayma Moukhachen, PharmD., BCPS, BCCCP

This module is provided free of charge. Registration is required to earn ACPE credit.


Release Date: March 14, 2022
Expiration Date: March 14, 2023
ACPE UAN: 0026-0000-22-001-H01-P Knowledge
Topic Designator: Drug Therapy
Contact Hours: 1 (0. 1 CEU)


ACPE logo

Massachusetts College of Pharmacy and Health Sciences is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Massachusetts College of Pharmacy and Health Sciences designates this activity for a total of 1 contact hour (0.1 CEU).

Requirements for Credit

In order to receive credit, the participant must view the entire presentation and complete the pre and post-tests, and evaluation form. Upon completion participant credit will be reported to CPE Monitor. Transcripts may be printed from CPE Monitor.

Statement of Disclosure

Massachusetts College of Pharmacy and Health Sciences adheres to the ACPE Standards for Integrity and Independence in Continuing Education. It is the policy of MCPHS that the speakers and planning committee members disclose all financial relationships with ineligible companies within the last 24 months, and that relevant conflicts of interest are mitigated. Speakers will disclose any off-label/unapproved use of drugs or devices during their presentation.

Shane Softy and Oussayma Moukhachen have no relevant financial relationships with ineligible companies to disclose.

Massachusetts College of Pharmacy and Health Sciences Continuing Education staff members hold no financial relationships with ineligible companies, related to the content of this presentation.

No funding from industry provided for this event. No exhibitors will be present.