Management Of Warfarin Coagulopathy For Non-Bleeding Patients In The Outpatient Setting: Overview Of Current Guidelines And Available Evidence

This CE will educate pharmacists on the most up-to-date information on management of supratherapeutic INRs in asymptomatic non-bleeding outpatients on warfarin therapy. Using in-depth discussions of current clinical practice recommendations, review of available data on patient outcomes, and practical discussions, the session will provide learners with knowledge to improve the care and outcomes for outpatients on warfarin therapy who experience asymptomatic supratherapeutic INR levels.

Learning Objectives

Upon completion of this activity, the participant will be able to:

  • Explain current guideline recommendations on use of Vitamin K in patients on warfarin therapy with supratherapeutic INR levels.
  • Compare risk factors that warrant vitamin K use versus no vitamin K use for non-bleeding outpatients with supratherapeutic INR levels due to warfarin therapy.


Aaminah Khan, PharmD, is the 2021-2022 MCPHS/Atrius Health PGY-1 pharmacy resident. Aaminah earned her Bachelor of Science in Physiological Science at University of California, Los Angeles followed by her Doctor of Pharmacy at MCPHS in Worcester, MA. Her professional interests include ambulatory and managed care, digital health, and chronic disease management.

Residency Mentor: Kathy Zaiken, PharmD, Professor of Pharmacy Practice

Registration Fee: This activity is free of charge to all.

Release Date: March 16, 2022
Expiration Date: March 16, 2023 
ACPE UAN: 0026-0000-22-002-H01-P | Knowledge
ACPE Topic Designator: Drug Therapy
Contact Hours: 1.0 (0.1 CEU)

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Massachusetts College of Pharmacy and Health Sciences is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Massachusetts College of Pharmacy and Health Sciences designates this activity for a total of 1.0 contact hour (0.1 CEUs).

To receive credit, participants must complete pre and post-assessments, view the entire presentation, and evaluate the session. Participant credit will be reported to the CPE Monitor upon conclusion. Transcripts may be printed from the CPE Monitor.

The policy of Massachusetts College of Pharmacy and Health Sciences is ensuring balance, independence, objectivity, and scientific rigor in all of its educational activities. Any individuals involved in planning or content creation for a continuing education activity are required to disclose financial relationships with ineligible companies that have occurred within the last 24 months. The intent of the policy is to identify and mitigate potential conflicts of interest that may affect the activity. All clinical medicine recommendations must be based on evidence accepted within the medical profession.

Aaminah Khan and Kathy Zaiken have no relevant financial relationships with ineligible companies to disclose.

Massachusetts College of Pharmacy and Health Sciences Continuing Education staff members hold no financial relationships with ineligible companies related to the content of this presentation.

Massachusetts College of Pharmacy and Health Sciences will identify, review, and mitigate all conflicts of interest disclosed prior to delivery of an educational activity to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation, but provides participants with information that may be of potential importance when they are evaluating content.